Product Description
Miconazole Nitrate
Brief Description
CAS No.: 22832-87-7
EINECS: 245-256-6
MW: 479.1414
Molecular Formula: C18H14Cl4N2O.HNO3
Other name: Miconazole Nitrate Powder
Grade: Medicine Grade
Standard: usp34
Type: Antibiotic and Antimicrobial l
Appearance: White or almost white powder
Shelf life: 2 Years
Package: 25kg/Fiber Drums
Purity: 99%min
MOQ: 25Kg
Specifications
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ITEMS |
SPECIFICATION |
RESULTS |
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Appearance |
White to almost white powders |
Complies |
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Appearance of Solution
|
The solution is clear and not more intensely colored than reference solutions Y7 |
Complies |
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Solubility
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Very slightly soluble in water; soluble in methanol; slightly soluble in alcohol |
Complies |
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Angle of optical rotation |
-0.1-------+0.1 |
0 |
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Related Substances |
Each Impurity |
≤ 0.25% |
0.19% |
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Total Impurity |
≤ 0.5% |
0.13% |
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Melting point |
178-184℃ |
182.2-183.7℃ |
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Loss on drying |
≤ 0.5% |
0.24% |
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Sulphated ash |
≤ 0.1% |
0.06%
|
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Residue solvents |
Toluene |
≤ 890ppm |
110ppm |
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Ethanol |
≤ 600ppm |
110ppm |
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Assay(on dry basis) |
99-101% |
99.4% |
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Conclusion：The items tested meet the requirements of USP34 |
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Usages:
Miconazole nitrate is an antifungal agent. This product at 4mg / L concentration can inhibit the growth of most fungi, buds, tissue plasmids are highly sensitive to its Cryptococcus, Candida, Coccidioides are also sensitive to the goods. Can interfere with the activity of cytochrome P-450, thereby inhibiting fungal cell membrane major steroids - ergosterol biosynthesis, damage the fungal cell membrane and change its permeability, so that important intracellular material leakage; also inhibit fungi Of the biosynthesis of triacylglycerol and phospholipids inhibit the activity of oxidase and peroxidase, causing accumulation of intracellular hydrogen peroxide leading to subcellular degeneration and cell necrosis. Candida albicans can inhibit its transformation from the spores into invasive mycelium process.
Packaging & Shipping
Packaging: 25kg/drum according to client request
Delivery details: 2 weeks after confirming order. Some of the products can be supplied within 7 days on the strength of EDC warehouse.
Company imformation:
Hubei Ipure chemical Co., Ltd. is Established in 2011,which is located in Wuhan We have decades of experience
The company is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of plant in accordance with GMP production requirements.
we also have a strong team of professional R&D technology.we have about 300 employees, including 90 full-time PHD 15 PHD and masters above, 153 undergraduates, with reasonable professional knowledge structure and adequate staffing.
The company has passed the ISO 9001 quality system certification. The products are exported to North America, South America, Europe, Australia Japan, Korea and other country . High quality products and good service are deeply trusted and praised by customers at home and abroad.
